International Review of Ophthalmology ›› 2013, Vol. 37 ›› Issue (4): 269-273.doi: 10.3706/ cma.j.issn.16735803.2013.04.012

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The role of müller cell in proliferative retinopathy

YANG Xiao, YUAN Yuan-sheng, ZHONG Hua   

  1. Department of Ophthalmology, First Affiliated Hospital of Kunming Medical University, Kunming 650032, China
  • Received:2012-12-02 Online:2013-08-22 Published:2013-09-03
  • Contact: ZHONG Hua, Email: zhoculist@163.com E-mail:zhoculist@163.com

Abstract: The retinal Müller cell is the principal glial cell of the vertebrate retina that responsible for the maintenance of the homeostasis of the retina. Müller cells play an important role in proliferative vitreoretinopathy (PVR) and proliferative diabetic retinopathy (PDR) through proliferation, migration, constriction, and changing of the cell phenotype. The potential roles of Müller cells in the pathogenesy and progression of PVR and PDR were reviewed as follow.